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Livres
Articles (41)
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The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao, Elinor Ng. Eaton, Ayyakkannu Ayyanan, Alicia Y. Zhou, Mary Brooks, Ferenc Reinhard, Cheng Cheng Zhang, Michail Shipitsin, Lauren L. Campbell, Kornelia Poly

Journal:

Cell

Année:

2008

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2008

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

Jing Yang, Sendurai A Mani, Joana Liu Donaher, Sridhar Ramaswamy, Raphael A Itzykson, Christophe Come, Pierre Savagner, Inna Gitelman, Andrea Richardson, Robert A Weinberg

Journal:

Cell

Année:

2004

Langue:

english

Fichier:

PDF, 740 KB

english, 2004

Synthesis of Fluorinated Graphene Oxide and its Amphiphobic Properties

Mathkar, Akshay, Narayanan, T. N., Alemany, Lawrence B., Cox, Paris, Nguyen, Patrick, Gao, Guanhui, Chang, Patricia, Romero-Aburto, Rebeca, Mani, Sendurai A., Ajayan, P. M.

Journal:

Particle & Particle Systems Characterization

Année:

2013

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2013

Molecular mechanisms of metastasis in breast cancer—clinical applications

Mego, Michal, Mani, Sendurai A., Cristofanilli, Massimo

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Année:

2010

Langue:

english

Fichier:

PDF, 333 KB

english, 2010

Sheep, wolf, or werewolf: Cancer stem cells and the epithelial-to-mesenchymal transition

Chang, Jeffrey T., Mani, Sendurai A.

Journal:

Cancer Letters

Année:

2013

Langue:

english

Fichier:

PDF, 517 KB

english, 2013

Fluorescent Superparamagnetic Iron Oxide Core–Shell Nanoprobes for Multimodal Cellular Imaging

Smitha, Sasidharan, Haseena, Vadakkenchery S., Narayanan, Tharangattu N., Reena Mary, Antony P., Ajayan, Pulickel M., Puthumana, Jayesh, Aziz, Anas A., Aburto, Rebeca R., Mani, Sendurai A., Joy, Patta

Journal:

Materials Express

Année:

2012

Langue:

english

Fichier:

PDF, 7.09 MB

english, 2012

3D Porous Graphene by Low-Temperature Plasma Welding for Bone Implants

Chakravarty, Dibyendu, Tiwary, Chandra Sekhar, Woellner, Cristano F., Radhakrishnan, Sruthi, Vinod, Soumya, Ozden, Sehmus, da Silva Autreto, Pedro Alves, Bhowmick, Sanjit, Asif, Syed, Mani, Sendurai A

Journal:

Advanced Materials

Année:

2016

Langue:

english

Fichier:

PDF, 3.05 MB

english, 2016

The Non-Coding RNA Journal Club: Highlights on Recent Papers—6

Xiao, Hua, Shiu, Patrick, Shu, Jun, Santulli, Gaetano, Gheybi, Mohammad, Conn, Simon, Bogard, Baptiste, Hubé, Florent, Taube, Joseph, Mani, Sendurai, Song, Luo, Calin, George, Zhang, Shuxing

Journal:

Non-Coding RNA

Année:

2018

Langue:

english

Fichier:

PDF, 227 KB

english, 2018

Epidermal growth factor down-regulates the expression of neutrophil gelatinase-associated lipocalin (NGAL) through E-cadherin in pancreatic cancer cells

Zhimin Tong, Subhankar Chakraborty, Bokyung Sung, Pooja Koolwal, Sukhwinder Kaur, Bharat B. Aggarwal, Sendurai A. Mani, Robert S. Bresalier, Surinder K. Batra, Sushovan Guha

Journal:

Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 562 KB

english, 2011

Expression of epithelial–mesenchymal transition-inducing transcription factors in primary breast cancer: The effect of neoadjuvant therapy

Michal Mego, Sendurai A. Mani, Bang-Ning Lee, Changping Li, Kurt W. Evans, Evan N. Cohen, Hui Gao, Summer A. Jackson, Antonio Giordano, Gabriel N. Hortobagyi, Massimo Cristofanilli, Anthony Lucci, Jam

Journal:

International Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 392 KB

english, 2012

Epithelial-Mesenchymal Transition-Derived Cells Exhibit Multilineage Differentiation Potential Similar to Mesenchymal Stem Cells

Venkata Lokesh Battula, Kurt William Evans, Brett George Hollier, Yuexi Shi, Frank C. Marini, Ayyakkannu Ayyanan, Rui-yu Wang, Cathrin Brisken, Rudy Guerra, Michael Andreeff, Sendurai A. Mani

Journal:

STEM CELLS

Année:

2010

Langue:

english

Fichier:

PDF, 715 KB

english, 2010

The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells: A Coalition Against Cancer Therapies

Brett G. Hollier, Kurt Evans, Sendurai A. Mani

Journal:

Journal of Mammary Gland Biology and Neoplasia

Année:

2009

Langue:

english

Fichier:

PDF, 327 KB

english, 2009

Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44hi/CD24lo/-Stem Cell Phenotype in Human Breast Cancer

Tony Blick, Honor Hugo, Edwin Widodo, Mark Waltham, Cletus Pinto, Sendurai A. Mani, Robert A. Weinberg, Richard M. Neve, Marc E. Lenburg, Erik W. Thompson

Journal:

Journal of Mammary Gland Biology and Neoplasia

Année:

2010

Langue:

english

Fichier:

PDF, 746 KB

english, 2010

The importance of the epithelial-mesenchymal transition in breast cancer

Nathalie Sphyris, Sendurai A. Mani

Journal:

Current Breast Cancer Reports

Année:

2009

Langue:

english

Fichier:

PDF, 354 KB

english, 2009

Hybrid 2D Nanomaterials as Dual-Mode Contrast Agents in Cellular Imaging

Tharangattu N. Narayanan, Bipin K. Gupta, Sajna A. Vithayathil, Rebeca R. Aburto, Sendurai A. Mani, Jaime Taha-Tijerina, Bin Xie, Benny A. Kaipparettu, Suzy V. Torti, Pulickel M. Ajayan

Journal:

Advanced Materials

Année:

2012

Langue:

english

Fichier:

PDF, 505 KB

english, 2012

Overexpression of Snail induces epithelial–mesenchymal transition and a cancer stem cell–like phenotype in human colorectal cancer cells

Fan Fan, Shaija Samuel, Kurt W. Evans, Jia Lu, Ling Xia, Yunfei Zhou, Eric Sceusi, Federico Tozzi, Xiang-Cang Ye, Sendurai A. Mani, Lee M. Ellis

Journal:

Cancer Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 539 KB

english, 2012

Alternative origins of stroma in normal organs and disease

Mikhail G. Kolonin, Kurt W. Evans, Sendurai A. Mani, Richard H. Gomer

Journal:

Stem Cell Research

Année:

2012

Langue:

english

Fichier:

PDF, 935 KB

english, 2012

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

Wenjun Guo, Zuzana Keckesova, Joana Liu Donaher, Tsukasa Shibue, Verena Tischler, Ferenc Reinhardt, Shalev Itzkovitz, Aurelia Noske, Ursina Zürrer-Härdi, George Bell, Wai Leong Tam, Sendurai A. Mani,

Journal:

Cell

Année:

2012

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2012

HDAC3 at the Fulcrum of an Epithelial-Mesenchymal Balance

Sendurai A. Mani, Michelle Craig Barton

Journal:

Molecular Cell

Année:

2011

Langue:

english

Fichier:

PDF, 157 KB

english, 2011

Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression

Caitlin D May, Nathalie Sphyris, Kurt W Evans, Steven J Werden, Wenjun Guo, Sendurai A Mani

Journal:

Breast Cancer Research

Année:

2011

Langue:

english

Fichier:

PDF, 602 KB

english, 2011

Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients

Erick Román-Pérez, Patricia Casbas-Hernández, Jason R Pirone, Jessica Rein, Lisa A Carey, Ronald A Lubet, Sendurai A Mani, Keith D Amos, Melissa A Troester

Journal:

Breast Cancer Research

Année:

2012

Langue:

english

Fichier:

PDF, 878 KB

english, 2012

Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer

Liu, Yanhong, Zhou, Renke, Baumbusch, Lars O., Tsavachidis, Spyros, Brewster, Abenaa M., Do, Kim-Anh, Sahin, Aysegul, Hortobagyi, Gabriel N., Taube, Joseph H., Mani, Sendurai A., Aarøe, Jørgen, Wärnbe

Journal:

Breast Cancer Research and Treatment

Année:

2014

Langue:

english

Fichier:

PDF, 355 KB

english, 2014

GD2 and GD3 synthase: novel drug targets for cancer therapy

Sphyris, Nathalie, Sarkar, Tapasree Roy, Battula, Venkata L, Andreeff, Michael, Mani, Sendurai A

Journal:

Molecular & Cellular Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2015

A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome

Soundararajan, Rama, Paranjape, Anurag N., Barsan, Valentin, Chang, Jeffrey T., Mani, Sendurai A.

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2015

Three-Dimensional Porous Sponges from Collagen Bio-Wastes

Meiyazhagan, Ashokkumar, Cristian Chipara, Alin, Tharangattu Narayanan, Narayanan, Ayyappan, Anumary, Radhakrishnan, Sruthi, Palanisamy, Thanikaivelan, Vajtai, Robert, A. Sendurai, Mani, Ajayan, Pulic

Journal:

ACS Applied Materials & Interfaces

Année:

2016

Langue:

english

Fichier:

PDF, 3.95 MB

english, 2016

Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype

Boareto, Marcelo, Jolly, Mohit Kumar, Goldman, Aaron, Pietilä, Mika, Mani, Sendurai A., Sengupta, Shiladitya, Ben-Jacob, Eshel, Levine, Herbert, Onuchic, Jose’ N.

Journal:

Journal of The Royal Society Interface

Année:

2016

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2016

Metal-Free Dual Modal Contrast Agents Based on Fluorographene Quantum Dots

Radhakrishnan, Sruthi, Samanta, Atanu, Sudeep, Parambath M., Maldonado, Kiersten L., Mani, Sendurai A., Acharya, Ghanashyam, Tiwary, Chandra Sekhar, Singh, Abhishek K., Ajayan, Pulickel M.

Journal:

Particle & Particle Systems Characterization

Année:

2016

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2016

Mathematical modelling of phenotypic plasticity and conversion to a stem-cell state under hypoxia

Dhawan, Andrew, Madani Tonekaboni, Seyed Ali, Taube, Joseph H., Hu, Stephen, Sphyris, Nathalie, Mani, Sendurai A., Kohandel, Mohammad

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2016

FOXC2 regulates the G2/M transition of stem cell-rich breast cancer cells and sensitizes them to PLK1 inhibition

Pietilä, Mika, Vijay, Geraldine V., Soundararajan, Rama, Yu, Xian, Symmans, William F., Sphyris, Nathalie, Mani, Sendurai A.

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2016

Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming

Tian, Lin, Goldstein, Amit, Wang, Hai, Ching Lo, Hin, Sun Kim, Ik, Welte, Thomas, Sheng, Kuanwei, Dobrolecki, Lacey E., Zhang, Xiaomei, Putluri, Nagireddy, Phung, Thuy L., Mani, Sendurai A., Stossi, F

Journal:

Nature

Année:

2017

Langue:

english

Fichier:

PDF, 15.66 MB

english, 2017

Targeting the Molecular Subtypes of Triple Negative Breast Cancer: Understanding the Diversity to Progress the Field

Yam, Clinton, Mani, Sendurai A., Moulder, Stacy L.

Journal:

The Oncologist

Année:

2017

Langue:

english

Fichier:

PDF, 280 KB

english, 2017

A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers

Bollong, Michael J., Pietilä, Mika, Pearson, Aaron D., Sarkar, Tapasree Roy, Ahmad, Insha, Soundararajan, Rama, Lyssiotis, Costas A., Mani, Sendurai A., Schultz, Peter G., Lairson, Luke L.

Journal:

Proceedings of the National Academy of Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2017

Tumor Cell Heterogeneity in Small Cell Lung Cancer (SCLC): Phenotypical and Functional Differences Associated with Epithelial-Mesenchymal Transition (EMT) and DNA Methylation Changes

Krohn, Alexander, Ahrens, Theresa, Yalcin, Arzu, Plönes, Till, Wehrle, Julius, Taromi, Sanaz, Wollner, Stefan, Follo, Marie, Brabletz, Thomas, Mani, Sendurai A., Claus, Rainer, Hackanson, Björn, Burge

Journal:

PLoS ONE

Année:

2014

Langue:

english

Fichier:

PDF, 3.00 MB

english, 2014

EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers

Soundararajan, Rama, Paranjape, Anurag N., Maity, Sankar, Aparicio, Ana, Mani, Sendurai A.

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 4.00 MB

english, 2018

Hybrid epithelial/mesenchymal phenotype(s): The ‘fittest’ for metastasis?

Jolly, Mohit Kumar, Mani, Sendurai A., Levine, Herbert

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 689 KB

english, 2018

The Non-Coding RNA Journal Club: Highlights on Recent Papers

Ferracin, Manuela, Gautheret, Daniel, Hubé, Florent, Mani, Sendurai, Mattick, John, Andersson Ørom, Ulf, Santulli, Gaetano, Slotkin, R., Szweykowska-Kulinska, Zofia, Taube, Joseph, Vazquez, Franck, Ya

Journal:

Non-Coding RNA

Année:

2015

Langue:

english

Fichier:

PDF, 245 KB

english, 2015

The Non-Coding RNA Journal Club: Highlights on Recent Papers—2

Francastel, Claire, Hubé, Florent, Mani, Sendurai, Santulli, Gaetano, Taube, Joseph, Szweykowska-Kulinska, Zofia

Journal:

Non-Coding RNA

Année:

2015

Langue:

english

Fichier:

PDF, 166 KB

english, 2015

The Non-Coding RNA Journal Club: Highlights on Recent Papers—4

Gautheret, Daniel, Taube, Joseph, Mani, Sendurai, Santulli, Gaetano, Cuerda-Gil, Diego, Slotkin, R., Zhang, Bo, Wang, Yanli, Salzman, David, Weidhaas, Joanne

Journal:

Non-Coding RNA

Année:

2016

Langue:

english

Fichier:

PDF, 190 KB

english, 2016

Erratum: The Non-Coding RNA Journal Club: Highlights on Recent Papers—4. Non-Coding RNA 2016, 2, 9

Gautheret, Daniel, Taube, Joseph, Mani, Sendurai, Santulli, Gaetano, Cuerda-Gil, Diego, Slotkin, R., Zhang, Bo, Wang, Yanli, Salzman, David, Weidhaas, Joanne

Journal:

Non-Coding RNA

Année:

2016

Langue:

english

Fichier:

PDF, 154 KB

english, 2016

Function of Tumor Suppressors in Resistance to Antiandrogen Therapy and Luminal Epithelial Plasticity of Aggressive Variant Neuroendocrine Prostate Cancers

Soundararajan, Rama, Aparicio, Ana M., Logothetis, Christopher J., Mani, Sendurai A., Maity, Sankar N.

Journal:

Frontiers in Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 251 KB

english, 2018

Stability of the hybrid epithelial/mesenchymal phenotype

Jolly, Mohit Kumar, Tripathi, Satyendra C., Jia, Dongya, Mooney, Steven M., Celiktas, Muge, Hanash, Samir M., Mani, Sendurai A., Pienta, Kenneth J., Ben-Jacob, Eshel, Levine, Herbert

Journal:

Oncotarget

Année:

2016

Langue:

english

Fichier:

PDF, 4.22 MB

english, 2016